Interaction with Meperidine Hydrocholoride, since the chemical structure of diphenoxylate hydrochloride is similar to that of meperidine hydrochloride, the concurrent use of Lomotil with monoamine oxidase (MAO) inhibitors may, in theory, precipitate hypertensive crisis. The safety and effectiveness of Lomotil have not been established in pediatric patients less htc u11 promo code canada than 13 years of age. This is not a complete list of side effects and others may occur. Not all possible drug interactions are listed here.
Teratology studies were conducted in rats, rabbits, and mice with diphenoxylate hydrochloride at oral doses.4 to 20 mg/kg/day. The relevance of this finding to usage of Lomotil in humans is unknown. Lomotil is a combination medicine used to treat diarrhea in adults and children who are at least 13 years old. Stop paying too much for your prescriptions. An overdose of atropine and diphenoxylate can be fatal to a child. See also: Side effects (in more detail) What other drugs will affect Lomotil? To use fluid and electrolyte therapy, if prescribed along with Lomotil, as instructed by their healthcare provider. Dehydration and Electrolyte Imbalance, the use of Lomotil should be accompanied by appropriate fluid and electrolyte therapy, when indicated.
Lomotil is contraindicated in pediatric patients less than 6 years of age due to the risks of severe respiratory depression and coma, possibly resulting in permanent brain damage or death (see contraindications ). Tell your doctor about all your other medicines. Call your doctor if you still have diarrhea after 10 days, or if you have a fever. Lomotil is contraindicated in: Pediatric patients less than 6 years of age due to the risks of respiratory and central nervous system (CNS) depression (see. Opioid) will present first or predominate; non-specific findings have been reported and include symptoms such as drowsiness (see. Diphenoxylate hydrochloride is chemically related to the narcotic analgesic meperidine. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. After a 5-mg oral dose of carbon-14 labeled diphenoxylate hydrochloride in ethanolic solution was given to three healthy volunteers, an average of 14 of the drug plus its metabolites was excreted in the urine and 49 in the feces over a four-day period. Treat all possible Lomotil overdosages as serious and maintain medical observation/hospitalization until patients become asymptomatic without naloxone use.
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