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triglyceride levels before you start taking kaletra and during your treatment. If you have advanced HIV-1 disease, you may have an increased risk of high triglyceride levels in your blood and pancreatitis. Tell your healthcare provider right away if you experience dizziness, lightheadedness, fainting, and/or a sensation of abnormal heartbeats. Do not start taking a new medicine without telling your doctor or pharmacist. Once daily kaletra dosing is not recommended in pregnancy see Use in Specific Populations (.1 ) and Clinical Pharmacology (.3 ). Total amounts of ethanol and propylene glycol from all medicines that are to be given to pediatric patients 14 days to 6 months of age should be taken into account in order to avoid toxicity from these excipients see Warnings and Precautions (.2 ). What are the possible side effects of kaletra? These are not all of the possible side effects of kaletra. Who should not take kaletra?

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Kaletra should not be taken once daily if you take carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Tegretol-XR, Teril phenobarbital, or phenytoin (Dilantin, Phenytek efavirenz (Atripla, Sustiva nevirapine (Viramune, Viramune XR or nelfinavir (Viracept). Kaletra once daily dosing regimen is not recommended in: Adult patients with three or more of the following lopinavir resistance-associated substitutions: L10F/I/R/V, K20M/N/R, L24I, L33F, M36I, I47V, G48V, I54L/T/V, V82A/C/F/S/T, and I84V see Microbiology (.4 ). Dosage Recommendations in Pregnancy Administer 400/100 mg of kaletra twice daily in pregnant patients with no documented lopinavir-associated resistance substitutions. Common side effects of kaletra include diarrhea, nausea, vomiting, and increased fats in blood (triglycerides or cholesterol). People who have high levels of a certain fat (triglycerides) have a risk for developing pancreatitis. There are insufficient data to recommend dosing in pregnant women with any documented lopinavir-associated resistance substitutions. Side effects in babies taking kaletra oral solution. Changes in your immune system (immune reconstitution syndrome) can happen when you start taking HIV-1 medicines. General Administration Recommendations, kaletra tablets may be taken with or without food. Do not breastfeed if you take kaletra. Feeding tubes that are compatible with ethanol and propylene glycol, such as silicone and polyvinyl chloride (PVC) feeding tubes, can be used for administration of kaletra oral solution.

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